Salicyloyl Phytosphingosine

INCI: SALICYLOYL PHYTOSPHINGOSINE

CAS Number
212908-67-3
Function
Skin conditioning, procollagen-I stimulation, ECM modulation, anti-inflammatory, barrier support
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not directly reviewed by CIR; registered in FDA GSRS. No specific FDA restrictions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Sphingolipid-based anti-aging active supported by read-across from ceramide derivatives but lacks standalone toxicological assessment.

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Concern Level: Low

Frequently Asked Questions

Is Salicyloyl Phytosphingosine safe in cosmetics?

Sphingolipid-based anti-aging active supported by read-across from ceramide derivatives but lacks standalone toxicological assessment. The EU classifies Salicyloyl Phytosphingosine as "permitted". Safety rating: GOOD.

Is Salicyloyl Phytosphingosine allowed in the EU?

Salicyloyl Phytosphingosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Salicyloyl Phytosphingosine do in cosmetics?

Salicyloyl Phytosphingosine functions as: Skin conditioning, procollagen-I stimulation, ECM modulation, anti-inflammatory, barrier support. It is classified as a cosmetic ingredient in our database. CAS number: 212908-67-3.

What is the Margin of Safety for Salicyloyl Phytosphingosine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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