Sanguinaria Canadensis Rhizome/Root Extract
INCI: SANGUINARIA CANADENSIS RHIZOME/ROOT EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
🚨 MAJOR SAFETY CONCERN. Sanguinarine (benzophenanthridine alkaloid) is cytotoxic, genotoxic, and linked to oral leukoplakia and eschar formation ("black salve" ingredient). Associated with severe tissue necrosis when used in "black salve" cancer quackery. Not recommended for cosmetic formulation. If used, requires strict alkaloid quantification and extremely low concentration limits. Some jurisdictions effectively prohibit its use
Regulatory Flags
Frequently Asked Questions
Is Sanguinaria Canadensis Rhizome/Root Extract safe in cosmetics?
🚨 MAJOR SAFETY CONCERN. Sanguinarine (benzophenanthridine alkaloid) is cytotoxic, genotoxic, and linked to oral leukoplakia and eschar formation ("black salve" ingredient). Associated with severe tissue necrosis when used in "black salve" cancer quackery. Not recommended for cosmetic formulation. If used, requires strict alkaloid quantification and extremely low concentration limits. Some jurisdictions effectively prohibit its use The EU classifies Sanguinaria Canadensis Rhizome/Root Extract as "permitted". Safety rating: POOR.
Is Sanguinaria Canadensis Rhizome/Root Extract allowed in the EU?
Sanguinaria Canadensis Rhizome/Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sanguinaria Canadensis Rhizome/Root Extract do in cosmetics?
Sanguinaria Canadensis Rhizome/Root Extract functions as: Cleansing, Refreshing, Skin Conditioning, Tonic. It is classified as a cosmetic ingredient in our database. CAS number: 84929-63-5.
What is the Margin of Safety for Sanguinaria Canadensis Rhizome/Root Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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