Sanguinaria Canadensis Root Extract

INCI: SANGUINARIA CANADENSIS ROOT EXTRACT (ALSO: SANGUINARIA CANADENSIS RHIZOME/ROOT EXTRACT)

CAS Number
84929-48-6
Function
Skin conditioning; the rhizome/root variant also: cleansing, refreshing, tonic
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; permitted for cosmetic use. Sanguinarine has been flagged in oral care

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains sanguinarine, a toxic alkaloid linked to tissue necrosis (black salve ingredient). Banned in food supplements in several EU jurisdictions. Canada Hotlist restricted. High caution for leave-on products.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Sanguinaria Canadensis Root Extract safe in cosmetics?

Contains sanguinarine, a toxic alkaloid linked to tissue necrosis (black salve ingredient). Banned in food supplements in several EU jurisdictions. Canada Hotlist restricted. High caution for leave-on products. The EU classifies Sanguinaria Canadensis Root Extract as "restricted". Safety rating: POOR.

Is Sanguinaria Canadensis Root Extract allowed in the EU?

Sanguinaria Canadensis Root Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sanguinaria Canadensis Root Extract do in cosmetics?

Sanguinaria Canadensis Root Extract functions as: Skin conditioning; the rhizome/root variant also: cleansing, refreshing, tonic. It is classified as a cosmetic ingredient in our database. CAS number: 84929-48-6.

What is the Margin of Safety for Sanguinaria Canadensis Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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