Is Sarcosyl (Sarcosine) safe in cosmetics?
Sarcosyl (Sarcosine) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Sarcosyl (Sarcosine)
Also known as: BRN 1699442, EINECS 203-538-6, UNII-Z711V88R5F, (Methylamino)acetate, (Methylamino)ethanoate (+14 more)
INCI: SARCOSINE
Sarcosyl (Sarcosine) (CAS 107-97-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 107-97-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-(methylamino)acetic acid
InChIKey
FSYKKLYZXJSNPZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; CIR has reviewed sarcosine-derived surfactants (e.g., Sodium Lauroyl Sarcosinate) and found them safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sarcosyl (Sarcosine).
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
2 property records from structured ingredient metadata.
acne
{"cas_number": "107-97-1", "anti_acne_mechanism": "sebum_regulation", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "non_inflammatory/hormonal", "sebum_reduction_pct_clinical": "15-30", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic…
anti_aging
{"anti_aging_claim": "hydration-plumping", "mechanism_of_action": "Specialized bioactive mechanism", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "5-10", "clinical_study_duration_weeks": "12", "sample_size": "28", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Specialized research journals…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
No indication of carcinogenicity (not listed by IARC). (L135)
Source: Toxin and Toxin Target Database (T3DB)
Carcinogen Classification
Not listed by IARC. Has been implicated in oncogenesis (A15089).
Source: Toxin and Toxin Target Database (T3DB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Sarcosyl (Sarcosine).
Known Synonyms
BRN 1699442
EINECS 203-538-6
UNII-Z711V88R5F
(Methylamino)acetate
(Methylamino)ethanoate
(methylamino)-Acetate
(methylamino)-Acetic acid
2-methylaminoacetic acid
2-methylaminoethanoic acid
L-sarcosine
MeGly
N-Methyl-Glycine
N-Methylaminoacetate
Sar
Sarcosinate
methylaminoacetic acid
(methylammonio)acetate
2-(methylazaniumyl)acetate
sarcosine zwitterion
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
SARCOSINE
ChEMBL ID
CHEMBL304383
Max Phase
2
Frequently Asked Questions
Is Sarcosyl (Sarcosine) allowed in the EU?
Sarcosyl (Sarcosine) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sarcosyl (Sarcosine) do in cosmetics?
Sarcosyl (Sarcosine) functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 107-97-1.
Is Sarcosyl (Sarcosine) used outside cosmetics?
Sarcosyl (Sarcosine) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sarcosyl (Sarcosine) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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