Semiaquilegia Adoxoides Root Extract

INCI: SEMIAQUILEGIA ADOXOIDES ROOT EXTRACT [^1_16]

CAS Number
223748-74-1 [^1_16]
Function
Skin conditioning [^1_16]
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ranunculaceae family โ€” potential protoanemonin content (vesicant). Very limited toxicological data. Used in Chinese folk medicine. Requires irritation/sensitization testing before formulation. [^1_16]

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Semiaquilegia Adoxoides Root Extract safe in cosmetics?

Ranunculaceae family โ€” potential protoanemonin content (vesicant). Very limited toxicological data. Used in Chinese folk medicine. Requires irritation/sensitization testing before formulation. [^1_16] The EU classifies Semiaquilegia Adoxoides Root Extract as "permitted". Safety rating: MODERATE.

Is Semiaquilegia Adoxoides Root Extract allowed in the EU?

Semiaquilegia Adoxoides Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Semiaquilegia Adoxoides Root Extract do in cosmetics?

Semiaquilegia Adoxoides Root Extract functions as: Skin conditioning [^1_16]. It is classified as a cosmetic ingredient in our database. CAS number: 223748-74-1 [^1_16].

What is the Margin of Safety for Semiaquilegia Adoxoides Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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