Is Sesamin safe in cosmetics?
Sesamin has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Antioxidant
Sesamin
Also known as: (+)-Sesamin, d-Sesamin, 1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo(3,4-c)furan-1,4-diyl)bis-, (1S-(1alpha,3a alpha,4alpha,6a alpha))-, 1H,3H-Furo(3,4-c)furan, tetrahydro-1,4-bis(3,4-(methylenedioxy)phenyl)-, (1S,3aR,4S,6aR)-
INCI: SESAMIN
Sesamin (CAS 607-80-7) is a cosmetic antioxidant functioning as Antioxidant, Skin Conditioning, Photoprotective, Anti-Inflammatory. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 607-80-7 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin Conditioning, Photoprotective, Anti-Inflammatory
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole
InChIKey
PEYUIKBAABKQKQ-AFHBHXEDSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restriction on sesamin in cosmetics. CIR Expert Panel (2011) concluded Sesamum indicum seed oil and related derivatives containing sesamin are safe.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sesamin.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Sesamin.
Known Synonyms
(+)-Sesamin
d-Sesamin
1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo(3,4-c)furan-1,4-diyl)bis-, (1S-(1alpha,3a alpha,4alpha,6a alpha))-
1H,3H-Furo(3,4-c)furan, tetrahydro-1,4-bis(3,4-(methylenedioxy)phenyl)-, (1S,3aR,4S,6aR)-
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
SESAMIN
ChEMBL ID
CHEMBL252915
Frequently Asked Questions
Is Sesamin allowed in the EU?
Sesamin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sesamin do in cosmetics?
Sesamin functions as: Antioxidant, Skin Conditioning, Photoprotective, Anti-Inflammatory. It is classified as a Antioxidant in our database. CAS number: 607-80-7.
Is Sesamin used outside cosmetics?
Sesamin also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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