SH-Hexapeptide-6 SP Amide

INCI: SH-HEXAPEPTIDE-6 SP AMIDE

CAS Number
Not publicly assigned
Function
Skin conditioning; the "amide" suffix indicates C-terminal amidation, which may enhance stability and bioactivity
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

C-terminal amidation can increase peptide half-life and receptor binding โ€” verify intended bioactivity matches safety profile; no independent review available

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Concern Level: Moderate

Frequently Asked Questions

Is SH-Hexapeptide-6 SP Amide safe in cosmetics?

C-terminal amidation can increase peptide half-life and receptor binding โ€” verify intended bioactivity matches safety profile; no independent review available The EU classifies SH-Hexapeptide-6 SP Amide as "permitted". Safety rating: MODERATE.

Is SH-Hexapeptide-6 SP Amide allowed in the EU?

SH-Hexapeptide-6 SP Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does SH-Hexapeptide-6 SP Amide do in cosmetics?

SH-Hexapeptide-6 SP Amide functions as: Skin conditioning; the "amide" suffix indicates C-terminal amidation, which may enhance stability and bioactivity. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for SH-Hexapeptide-6 SP Amide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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