Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Distinguish clearly between SH-Hexapeptide-8 SP and Acetyl Hexapeptide-8 (Argireline®) — they are not interchangeable INCI names; verify supplier's sequence matches intended bioactivity
Frequently Asked Questions
Is SH-Hexapeptide-8 SP safe in cosmetics?
Distinguish clearly between SH-Hexapeptide-8 SP and Acetyl Hexapeptide-8 (Argireline®) — they are not interchangeable INCI names; verify supplier's sequence matches intended bioactivity The EU classifies SH-Hexapeptide-8 SP as "permitted". Safety rating: GOOD.
Is SH-Hexapeptide-8 SP allowed in the EU?
SH-Hexapeptide-8 SP EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does SH-Hexapeptide-8 SP do in cosmetics?
SH-Hexapeptide-8 SP functions as: Skin conditioning; the parent Hexapeptide-8 (Argireline base) is an anti-wrinkle peptide targeting neuromuscular signaling. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for the SH- SP variant (parent Hexapeptide-8: 304432-12-0).
What is the Margin of Safety for SH-Hexapeptide-8 SP?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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