Is SH-Hexapeptide-8 SP safe in cosmetics?
SH-Hexapeptide-8 SP has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
SH-Hexapeptide-8 SP
INCI: SH-HEXAPEPTIDE-8 SP
SH-Hexapeptide-8 SP (CAS Not publicly assigned for the SH- SP variant (parent Hexapeptide-8: 304432-12-0)) is a cosmetic cosmetic ingredient functioning as Skin conditioning; the parent Hexapeptide-8 (Argireline base) is an. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly assigned for the SH- SP variant (parent Hexapeptide-8: 304432-12-0)
View industrial chemical safety profile →
Function
Skin conditioning; the parent Hexapeptide-8 (Argireline base) is an anti-wrinkle peptide targeting neuromuscular signaling
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restriction; parent compound widely used in US market
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for SH-Hexapeptide-8 SP.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for SH-Hexapeptide-8 SP.
Frequently Asked Questions
Is SH-Hexapeptide-8 SP allowed in the EU?
SH-Hexapeptide-8 SP EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does SH-Hexapeptide-8 SP do in cosmetics?
SH-Hexapeptide-8 SP functions as: Skin conditioning; the parent Hexapeptide-8 (Argireline base) is an anti-wrinkle peptide targeting neuromuscular signaling. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for the SH- SP variant (parent Hexapeptide-8: 304432-12-0).
Compliance Tools
Check SH-Hexapeptide-8 SP compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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