Is SH-Hexapeptide-4 safe in cosmetics?
SH-Hexapeptide-4 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
SH-Hexapeptide-4
INCI: SH-HEXAPEPTIDE-4
SH-Hexapeptide-4 (CAS Not publicly assigned for the SH- variant (parent Hexapeptide-4: 112317-45-0)) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly assigned for the SH- variant (parent Hexapeptide-4: 112317-45-0)
View industrial chemical safety profile →
Function
Skin conditioning
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
No specific FDA monograph; permitted under general cosmetic ingredient provisions (no pre-market approval required)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for SH-Hexapeptide-4.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for SH-Hexapeptide-4.
Frequently Asked Questions
Is SH-Hexapeptide-4 allowed in the EU?
SH-Hexapeptide-4 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does SH-Hexapeptide-4 do in cosmetics?
SH-Hexapeptide-4 functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for the SH- variant (parent Hexapeptide-4: 112317-45-0).
Compliance Tools
Check SH-Hexapeptide-4 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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