Silk

INCI: SILK (ALSO: SILK POWDER, HYDROLYZED SILK, SILK EXTRACT โ€” DISTINCT INCI ENTRIES)

CAS Number
96690-41-4 (Silk); related: 96690-41-4 (Silk Powder)
Function
Skin conditioning; hair conditioning; bulking agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted. CIR reviewed 10 silk protein ingredients โ€” concluded safe as used . Silk (Fibroin) also FDA-approved as surgical suture material

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Inhalation concern for powder forms (face powders up to 1.4%); particle size matters for respirable fraction. Type I silk allergy is rare but documented. Hydrolyzed low-MW variants pose higher sensitization risk than intact protein

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Silk safe in cosmetics?

Inhalation concern for powder forms (face powders up to 1.4%); particle size matters for respirable fraction. Type I silk allergy is rare but documented. Hydrolyzed low-MW variants pose higher sensitization risk than intact protein The EU classifies Silk as "permitted". Safety rating: GOOD.

Is Silk allowed in the EU?

Silk EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Silk do in cosmetics?

Silk functions as: Skin conditioning; hair conditioning; bulking agent. It is classified as a cosmetic ingredient in our database. CAS number: 96690-41-4 (Silk); related: 96690-41-4 (Silk Powder).

What is the Margin of Safety for Silk?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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