Regulatory Status
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Safety Data
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Expert Verdict
✅ Generally safe; perform patch test for sensitive individuals; GHS classification of silymarin (parent complex) notes H315/H319 skin/eye irritation at concentrate level — not relevant at typical cosmetic use concentrations
Frequently Asked Questions
Is Silybin safe in cosmetics?
✅ Generally safe; perform patch test for sensitive individuals; GHS classification of silymarin (parent complex) notes H315/H319 skin/eye irritation at concentrate level — not relevant at typical cosmetic use concentrations The EU classifies Silybin as "permitted". Safety rating: EXCELLENT.
Is Silybin allowed in the EU?
Silybin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Silybin do in cosmetics?
Silybin functions as: Antioxidant, skin conditioning, anti-aging (major active flavonolignan from milk thistle / *Silybum marianum*). It is classified as a cosmetic ingredient in our database. CAS number: 22888-70-6.
What is the Margin of Safety for Silybin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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