Regulatory Status
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Safety Data
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Expert Verdict
✅ Generally safe and well-tolerated; clinical evidence supports anti-aging claims (increased collagen III by 23% vs bakuchiol, reduced wrinkle count by 21%); ensure supplier documentation confirms absence of pesticides/heavy metals (standard for plant cell culture extracts)
Regulatory Flags
Frequently Asked Questions
Is Silybum Marianum Callus Extract safe in cosmetics?
✅ Generally safe and well-tolerated; clinical evidence supports anti-aging claims (increased collagen III by 23% vs bakuchiol, reduced wrinkle count by 21%); ensure supplier documentation confirms absence of pesticides/heavy metals (standard for plant cell culture extracts) The EU classifies Silybum Marianum Callus Extract as "permitted". Safety rating: EXCELLENT.
Is Silybum Marianum Callus Extract allowed in the EU?
Silybum Marianum Callus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Silybum Marianum Callus Extract do in cosmetics?
Silybum Marianum Callus Extract functions as: Skin conditioning, antioxidant, anti-aging (plant stem cell extract from milk thistle callus culture; rich in silymarin complex including silybin). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (plant cell culture extract).
What is the Margin of Safety for Silybum Marianum Callus Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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