Moderate Cosmetic Ingredient NOAEL Data

Sodium Benzotriazolyl Butylphenol Sulfonate

INCI: SODIUM BENZOTRIAZOLYL BUTYLPHENOL SULFONATE

Sodium Benzotriazolyl Butylphenol Sulfonate (CAS 92484-48-5) is a cosmetic cosmetic ingredient functioning as UV absorber / UV filter (water-soluble benzotriazole derivative). Reported NOAEL =200 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 92484-48-5 →

Auto-generated CPSR Part A draft with source citations
Function
UV absorber / UV filter (water-soluble benzotriazole derivative)
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C16H16N3NaO4S
MW
369.4 g/mol
EC Number
403-080-9
PubChem CID
23690892
IUPAC Name
sodium 3-(benzotriazol-2-yl)-5-butan-2-yl-4-hydroxybenzenesulfonate
InChIKey
XTXADMXOEMEPAC-UHFFFAOYSA-M

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not listed as an approved OTC sunscreen active by FDA; may be used as a non-active cosmetic UV stabilizer/protector at manufacturer's discretion under cosmetic regulations

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Benzotriazolyl Butylphenol Sulfonate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Sodium Benzotriazolyl Butylphenol Sulfonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =200 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Danger
Pictograms
Corrosive
Hazard Class and Category
Eye Dam. 1
Hazard Statements
  • H318 Causes serious eye damage

Inserted via ATP: CLP00

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance Surfactant (surface active agent) UV stabilizer
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Sodium Benzotriazolyl Butylphenol Sulfonate.

Regulatory Flags

ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Sodium Benzotriazolyl Butylphenol Sulfonate by CAS number or substance name.

Studies
1
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
200 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

Surfactant (surface active agent) UV stabilizer Fragrance

Regulatory Lists

IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Sodium Benzotriazolyl Butylphenol Sulfonate safe in cosmetics?

Sodium Benzotriazolyl Butylphenol Sulfonate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Sodium Benzotriazolyl Butylphenol Sulfonate allowed in the EU?

Sodium Benzotriazolyl Butylphenol Sulfonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Benzotriazolyl Butylphenol Sulfonate do in cosmetics?

Sodium Benzotriazolyl Butylphenol Sulfonate functions as: UV absorber / UV filter (water-soluble benzotriazole derivative). It is classified as a cosmetic ingredient in our database. CAS number: 92484-48-5.

What is the NOAEL for Sodium Benzotriazolyl Butylphenol Sulfonate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Benzotriazolyl Butylphenol Sulfonate is =200 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

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