Is Sodium Bisulfate safe in cosmetics?
Sodium Bisulfate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Sodium Bisulfate
INCI: SODIUM BISULFATE
Sodium Bisulfate (CAS 7681-38-1) is a cosmetic cosmetic ingredient functioning as pH adjuster; buffering agent. EU Regulation 1223/2009 status: restricted, max 0.2%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 7681-38-1 →
Auto-generated CPSR Part A draft with source citations
Function
pH adjuster; buffering agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
sodium hydrogen sulfate
InChIKey
WBHQBSYUUJJSRZ-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.2%
US US Status
permitted
US Notes
GRAS (Generally Recognized as Safe) for food contact; permitted in cosmetics as pH adjuster; no specific FDA restriction for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Bisulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Bisulfate.
Regulatory Flags
epa_safer_alternative
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1200488
Frequently Asked Questions
Is Sodium Bisulfate allowed in the EU?
Sodium Bisulfate EU regulatory status: restricted. Maximum allowed concentration: 0.2%. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Bisulfate do in cosmetics?
Sodium Bisulfate functions as: pH adjuster; buffering agent. It is classified as a cosmetic ingredient in our database. CAS number: 7681-38-1.
Is Sodium Bisulfate used outside cosmetics?
Sodium Bisulfate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Bisulfate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Sodium Bisulfate in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Bisulfate in your formulation.