Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Sodium C10-13 Alkyl Benzenesulfonate

INCI: SODIUM C10-13 ALKYL BENZENESULFONATE

CAS Number
68411-30-3
Function
Surfactant – Cleansing (linear alkylbenzene sulfonate, LAS)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; no specific restrictions; included in Skin Cleansing category

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Sodium C10-13 Alkyl Benzenesulfonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 250 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 280 mg/kg bw/day oral dog Subchronic COSMOS_DB
NOAEL 180 mg/kg bw/day oral dog Chronic COSMOS_DB
NOAEL 250 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 250 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 250 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB
NOAEL 250 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB
NOAEL 300 mg/kg bw/day oral rabbit Developmental COSMOS_DB
NOAEL 600 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 300 mg/kg bw/day oral mouse Developmental COSMOS_DB

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is corrosive to the eyes. The substance is irritating to the skin and respiratory tract.
Routes of Exposure
The substance can be absorbed into the body by ingestion.

Expert Verdict

H302 (harmful if swallowed), H315 (skin irritation), H318 (serious eye damage), H412 (aquatic toxicity); chain distribution C10:C11:C12:C13 ≈ 13:30:33:24; primarily for rinse-off only

⚠️
Concern Level: High

Frequently Asked Questions

Is Sodium C10-13 Alkyl Benzenesulfonate safe in cosmetics?

H302 (harmful if swallowed), H315 (skin irritation), H318 (serious eye damage), H412 (aquatic toxicity); chain distribution C10:C11:C12:C13 ≈ 13:30:33:24; primarily for rinse-off only The EU classifies Sodium C10-13 Alkyl Benzenesulfonate as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.

Is Sodium C10-13 Alkyl Benzenesulfonate allowed in the EU?

Sodium C10-13 Alkyl Benzenesulfonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium C10-13 Alkyl Benzenesulfonate do in cosmetics?

Sodium C10-13 Alkyl Benzenesulfonate functions as: Surfactant – Cleansing (linear alkylbenzene sulfonate, LAS). It is classified as a cosmetic ingredient in our database. CAS number: 68411-30-3.

What is the Margin of Safety for Sodium C10-13 Alkyl Benzenesulfonate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium C10-13 Alkyl Benzenesulfonate?

The NOAEL (No Observed Adverse Effect Level) for Sodium C10-13 Alkyl Benzenesulfonate is 250 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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