Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for C12-15 Alkyl Benzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >8 other | oral | rat | oral | REACH |
| NOAEL | 2 other | oral | rat | oral | REACH |
| NOAEL | >8 other | oral | rat | oral | REACH |
| NOAEL | 2 other | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | dog | oral | REACH |
Expert Verdict
C12-15 Alkyl Benzoate has a clean regulatory profile with no Annex restrictions, no concentration limits, and rapid metabolic conversion to benzoic acid (GRAS); 2025 GLP dermal absorption data supports safety for conventional and natural-origin formulations.
Frequently Asked Questions
Is C12-15 Alkyl Benzoate safe in cosmetics?
C12-15 Alkyl Benzoate has a clean regulatory profile with no Annex restrictions, no concentration limits, and rapid metabolic conversion to benzoic acid (GRAS); 2025 GLP dermal absorption data supports safety for conventional and natural-origin formulations. The EU classifies C12-15 Alkyl Benzoate as "permitted". Safety rating: EXCELLENT. 7 toxicological study endpoint(s) are available in our database.
Is C12-15 Alkyl Benzoate allowed in the EU?
C12-15 Alkyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does C12-15 Alkyl Benzoate do in cosmetics?
C12-15 Alkyl Benzoate functions as: skin conditioning - emollient, solvent, UV filter solubilizer. It is classified as a Emollient in our database. CAS number: 68411-27-8.
What is the Margin of Safety for C12-15 Alkyl Benzoate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for C12-15 Alkyl Benzoate?
The NOAEL (No Observed Adverse Effect Level) for C12-15 Alkyl Benzoate is >=1200 mg/kg bw/day based on a oral study via oral route in rat. A total of 7 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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