Excellent Emollient NOAEL Data

C12-15 Alkyl Benzoate

INCI: C12-15 ALKYL BENZOATE

C12-15 Alkyl Benzoate (CAS 68411-27-8) is a cosmetic emollient functioning as skin conditioning - emollient, solvent, UV filter solubilizer. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 68411-27-8 →

Auto-generated CPSR Part A draft with source citations
Function
skin conditioning - emollient, solvent, UV filter solubilizer
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
270-112-4

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR concluded safe at present practices of use and concentration; 971 VCRP product uses (858 leave-on, 113 rinse-off); no FDA restrictions; not an OTC sunscreen active

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for C12-15 Alkyl Benzoate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for C12-15 Alkyl Benzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for C12-15 Alkyl Benzoate across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Face Cream 2–5 20 CIR/VCRP
Sunscreen 3–10 20 CIR/VCRP

Additional Ingredient Properties

9 property records from structured ingredient metadata.

comedogenicity_detail
{"comedogenicity_rating": "2", "irritancy_rating": "0", "skin_type_suitability": "all,combination,normal", "acne_safe": "caution", "source": "Synthetic ester"}
cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "18", "estimated_cost_per_kg_usd_high": "32", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "low", "primary_source_region": "Global", "bulk_discount_threshold_kg": "200", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Phenyl Trimeth…
ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "90-180", "bioaccumulative": "yes", "aquatic_toxicity_level": "low", "coral_reef_safe": "unknown", "marine_toxicity": "low-moderate toxicity", "freshwater_toxicity": "moderate persistence", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environm…
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "11-12", "co_emulsifier_pairs": "polysorbate_80,ceteth_20", "optimal_oil_phase_pct": "10-30", "optimal_water_phase_pct": "70-90", "droplet_size_range_um": "1-20", "creaming_resistance": "good", "coalescence_resistance": "good", "ostwald_ripening_resistance": "moderate", "freeze_thaw_stability": "moderate", "rheology_modifier_type": …
hair_care
{"hair_function": "moisturizing", "hair_type_suitability": "fine/medium", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "yes", "heat_protectant": "yes", "color_safe": "neutra…
lipid
{"cas_number": "68411-27-8", "lipid_class": "ester", "botanical_source": "synthetic/derived", "plant_part": "derived", "extraction_method": "refined", "fatty_acid_profile_main_pct": "aromatic ester", "omega_classification": "saturated", "comedogenicity_rating_0_5": "0-2", "absorption_rate": "fast", "skin_feel": "dry", "spreadability": "excellent", "occlusive_properties": "low", "emollient_grade": …
sensory
{"silky": "light", "smooth, glides easily": "silky, elegant", "dry-touch, non-greasy": "dry, powdery", "instant": "fast", "low": "low", "w/o": "o/w", "very-high": "excellent", "no": "no", "yes": "no", "1.40": "1.48", "transparent": "transparent", "colorless": "colorless", "excellent": "excellent", "light": "light", "synthetic": "synthetic"}
solubility_hlb
{"water_soluble": "no", "oil_soluble": "yes", "hlb_required": "5.0", "soluble_in": "oils, ethanol", "insoluble_in": "water, glycerin, propylene glycol", "log_p": "5.8", "melting_point_c": "-25", "appearance": "clear liquid", "source": "Vantage"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Biocide Emulsifier Fragrance Softener and conditioner Solvent Surfactant (surface active agent) Wetting agent (non-aqueous)
Regulatory List Membership (2)
EU Regulated in Personal Care Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for C12-15 Alkyl Benzoate.

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to C12-15 Alkyl Benzoate by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

Softener and conditioner Emulsifier Biocide

Regulatory Lists

inert_ingredient; non_food_use; Pesticides Europe; Personal care Europe; Personal care Europe; Personal care consumer_product

Australian Status

AICIS status: listed

Frequently Asked Questions

Is C12-15 Alkyl Benzoate safe in cosmetics?

C12-15 Alkyl Benzoate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is C12-15 Alkyl Benzoate allowed in the EU?

C12-15 Alkyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does C12-15 Alkyl Benzoate do in cosmetics?

C12-15 Alkyl Benzoate functions as: skin conditioning - emollient, solvent, UV filter solubilizer. It is classified as a Emollient in our database. CAS number: 68411-27-8.

What is the NOAEL for C12-15 Alkyl Benzoate?

The NOAEL (No Observed Adverse Effect Level) for C12-15 Alkyl Benzoate is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is C12-15 Alkyl Benzoate used outside cosmetics?

C12-15 Alkyl Benzoate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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