Is Sodium Carboxymethyl Cellulose safe in cosmetics?
Sodium Carboxymethyl Cellulose has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Sodium Carboxymethyl Cellulose
Also known as: B 10, AC-Di-sol. NF, Camellose gum, Carmellose gum, Carmethose (+14 more)
INCI: SODIUM CARBOXYMETHYL CELLULOSE
Sodium Carboxymethyl Cellulose (CAS 9004-32-4) is a cosmetic cosmetic ingredient functioning as Emulsifier. EU Regulation 1223/2009 status: permitted, max 20%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 9004-32-4 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifier
Safety Rating
GOOD
Chemistry & Identifiers
EC Number
618-378-6
Regulatory Status
EU EU Status
permitted
EU Max Conc.
20%
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Carboxymethyl Cellulose.
Calculate MoS for your specific formulation with the MoS Calculator.
EPA ToxValDB — Toxicity Values
6 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LC50 | >5.8 mg/L | Rat | inhalation | - | ChemIDplus |
| LD50 | =16000 mg/kg | Guinea Pig | oral | - | ChemIDplus |
| LD50 | >27000 mg/kg | Mouse | oral | - | ChemIDplus |
| LD50 | >27000 mg/kg | Rabbit | oral | - | ChemIDplus |
| LD50 | >2000 mg/kg | Rabbit | dermal | - | ChemIDplus |
| LD50 | =27000 mg/kg | Rat | oral | - | ChemIDplus |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter
Anti-caking agent
Anti-redeposition agent
Binder
Chelating agent
Deodorizer
Drier
Emulsifier
Film former
Fragrance
Regulatory List Membership (3)
EU Restricted for Children (Cosmetics)
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Carboxymethyl Cellulose.
Regulatory Flags
eu_children_restricted
epa_safer_alternative
fda_food_additive
jecfa_safe
Known Synonyms
B 10
AC-Di-sol. NF
Camellose gum
Carmellose gum
Carmethose
Cellofas B
Cellofas B5
Cellofas B50
Cellofas B6
Cellulose glycolic acid, sodium salt
NaCm-cellulose salt
Sanlose SN 20A
Sodium carboxmethylcellulose
Sodium carboxymethylcellulose
Sodium salt of carboxymethylcellulose
Tylose CB series
Tylose CBR series
Tylose CR
UNII-0891BL4S3D
Chemical Function
Viscosity modifier
Anti-redeposition agent
Binder
Regulatory Lists
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe; Personal care - oral and dental care - teeth whitener
inert_ingredient; Pesticides
children; Europe; Personal care
children; Europe; Personal care - dental care - toothpaste
Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe
Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe
Cleaning products and household care; Europe
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
SCIL (9/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
1548
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Sodium carboxymethyl cellulose
E Number
E466
ADI
NOT SPECIFIED mg/kg bw
Food Category
emulsifier
Frequently Asked Questions
Is Sodium Carboxymethyl Cellulose allowed in the EU?
Sodium Carboxymethyl Cellulose EU regulatory status: permitted. Maximum allowed concentration: 20%. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Carboxymethyl Cellulose do in cosmetics?
Sodium Carboxymethyl Cellulose functions as: Emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: 9004-32-4.
Is Sodium Carboxymethyl Cellulose used outside cosmetics?
Sodium Carboxymethyl Cellulose also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Carboxymethyl Cellulose compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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