Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Sodium Casein. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 190 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 1600 mg/kg bw/day | oral | mouse | Developmental | COSMOS_DB |
| dose_tested | 1600 mg/kg bw/day | oral | mouse | Developmental | COSMOS_DB |
Expert Verdict
Milk protein origin requires allergen labeling and safety assessment; contraindicated for individuals with confirmed casein or milk allergy.
Regulatory Flags
Frequently Asked Questions
Is Sodium Casein safe in cosmetics?
Milk protein origin requires allergen labeling and safety assessment; contraindicated for individuals with confirmed casein or milk allergy. The EU classifies Sodium Casein as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is Sodium Casein allowed in the EU?
Sodium Casein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Casein do in cosmetics?
Sodium Casein functions as: Hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 9005-46-3.
What is the Margin of Safety for Sodium Casein?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Casein?
The NOAEL (No Observed Adverse Effect Level) for Sodium Casein is 190 mg/kg bw/day based on a Developmental study via oral route in rabbit. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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