Poor Cosmetic Ingredient NOAEL Data GHS Classified

Sodium Chlorate

INCI: SODIUM CHLORATE

CAS Number
7775-09-9
Function
Oxidizing agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 3%
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not specifically prohibited; regulated under general cosmetic safety provisions; limited use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Sodium Chlorate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 100 mg/kg bw/day oral rat oral REACH
NOAEL 200 mg/kg bw/day other dog other REACH
NOAEL 160 mg/kg bw/day oral mouse oral REACH
NOAEL 5 mg/kg bw/day oral rat oral REACH
NOAEL 38 mg/kg bw/day oral rat oral REACH
NOAEL 100 mg/kg bw/day oral rat oral REACH
NOAEL 360 mg/kg bw/day oral dog oral REACH
NOAEL 55 mg/kg bw/day oral rat oral REACH
NOAEL 35 mg/kg bw/day oral rat oral REACH
NOAEL 365 mg/kg bw/day oral mouse oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
flam circle; cancer;health haz; excl mark;warn
Hazard Statements
May cause fire or explosion; strong oxidizer Harmful if swallowed Causes damage to blood and kidneys
Short-term Exposure Effects
The substance is mildly irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The substance may cause effects on the kidneys. This may result in kidney impairment. The effects may be delayed. See Notes. Medical observation is indicated.
Long-term Exposure Effects
The substance may have effects on the thyroid. This may result in impaired functions.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Expert Verdict

Strong oxidizer; causes methemoglobinemia at systemic doses; hemolytic potential; restricted to hair dyes only in EU; must not be used in oral care or leave-on products

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Concern Level: High

Frequently Asked Questions

Is Sodium Chlorate safe in cosmetics?

Strong oxidizer; causes methemoglobinemia at systemic doses; hemolytic potential; restricted to hair dyes only in EU; must not be used in oral care or leave-on products The EU classifies Sodium Chlorate as "restricted". Safety rating: POOR. 10 toxicological study endpoint(s) are available in our database.

Is Sodium Chlorate allowed in the EU?

Sodium Chlorate EU regulatory status: restricted. Maximum allowed concentration: 3%. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Chlorate do in cosmetics?

Sodium Chlorate functions as: Oxidizing agent. It is classified as a cosmetic ingredient in our database. CAS number: 7775-09-9.

What is the Margin of Safety for Sodium Chlorate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium Chlorate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Chlorate is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

Is Sodium Chlorate classified as hazardous under GHS?

Sodium Chlorate carries a GHS signal word of "DANGER". Hazard statements: May cause fire or explosion; strong oxidizer Harmful if swallowed Causes damage to blood and kidneys. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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