Is Sodium Chlorate safe in cosmetics?
Sodium Chlorate has a safety rating of "POOR" in our database. EU status: restricted. US status: prohibited. 10 toxicological study endpoint(s) are available in our database.
Sodium Chlorate
Also known as: Chloric acid, sodium salt, Chloric acid, sodium salt (1:1), Agrosan, Caswell No. 753, Drexel defol (+15 more)
INCI: SODIUM CHLORATE
Sodium Chlorate (CAS 7775-09-9) is a cosmetic cosmetic ingredient functioning as Oxidizing agent. NOAEL 10 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max 3%; GHS signal word DANGER. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7775-09-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Sodium Chlorate is classified GHS Danger (H271, H302, H411, H272, H332) in the chemicals database but is restricted in EU cosmetics at max 3%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Oxidizing agent
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
sodium chlorate
InChIKey
YZHUMGUJCQRKBT-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
EU Max Conc.
3%
US US Status
prohibited
US Notes
Not specifically prohibited; regulated under general cosmetic safety provisions; limited use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Chlorate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Sodium Chlorate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.003 mg/kg bw/day | oral | Rat | Carcinogenicity | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =0.003 mg/kg bw/day | oral | Rat | Carcinogenicity | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =3 mg/kg bw/day | - | - | Toxicology study | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =3 mg/kg bw/day | - | - | Toxicology study | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =7.4 mg/kg bw/day | oral | Rat | Subchronic toxicity | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =7.4 mg/kg bw/day | oral | Rat | Subchronic toxicity | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =30 mg/kg bw/day | - | - | Toxicology study | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =30 mg/kg bw/day | - | - | Toxicology study | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =360 mg/kg bw/day | - | - | Toxicology study | INCHEM_WHO_jecfa_jecmono_v59je01 |
| NOAEL | =360 mg/kg bw/day | - | - | Toxicology study | INCHEM_WHO_jecfa_jecmono_v59je01 |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Signal Word
DANGER
Pictograms
Flam circleCancerHealth hazExcl markWarn
Hazard Statements
May cause fire or explosion; strong oxidizer Harmful if swallowed Causes damage to blood and kidneys
Short-term Exposure Effects
The substance is mildly irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The substance may cause effects on the kidneys. This may result in kidney impairment. The effects may be delayed. See Notes. Medical observation is indicated.
Long-term Exposure Effects
The substance may have effects on the thyroid. This may result in impaired functions.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Sodium Chlorate across SCCS product categories, with measured dermal absorption where available.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
OxidiserAcute Toxicity
Hazard Class and Category
Ox. Sol. 1; Acute Tox. 3
Hazard Statements
- H271 May cause fire or explosion; strong oxidiser
- H301 Toxic if swallowed
Specific Concentration Limits / M-factors
oral: ATE = 100.0 mg/kg bw
Inserted via ATP: ATP21
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Suspected
Evidence: Moderate
(2025)
Health effects: Yes
Affected pathways: Thyroid (iodine uptake inhibition)
Regulatory framework: REACH
Source list: II
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | restricted | 5 (dentifrices) / 3 (others) | a) Dentifrices: 5%; b) Other cosmetic uses: 3% |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (3)
Carcinogen Classification
Water Disinfection Byproducts (Sodium Chlorate) | TR-517: Toxicology and Carcinogenesis Studies of Sodium Chlorate (CASRN 7775-09-9) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) (2005 ) | 12/09/04 | Some Evidence | Some Evidence | No Evidence | Equivocal Evidence | Under the conditions of this 2-year drinking water study, there was some evidence of carcinogenic activity of so
Source: NTP Technical Reports
ICSC Safety Card
1117
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
Sodium chlorate is irritating to skin, eyes, and mucous membranes of the upper respiratory tract. | Vapors from this material may cause nose, throat and lung irritation. /Sodium chlorate (Environmentally hazardous substances, liquid, NOS)/
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Bleaching agent
Chemical reaction regulator
Deodorizer
Oxidizing agent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Chlorate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Sodium Chlorate by CAS number or substance name.
Studies
64
Lowest NOAEL
0.003 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
INCHEM_WHO_jecfa_jecmono_v59je01
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Chloric acid, sodium salt
Chloric acid, sodium salt (1:1)
Agrosan
Caswell No. 753
Drexel defol
Drop-Leaf
EINECS 231-887-4
EPA Pesticide Chemical Code 073301
Grain sorghum harvest-aid
Harvest-aid
Hibar C
Kusatol
Ortho C-1 defoliant & weed killer
Ortho-C-1-Defoliant
Rasikal
Shed-A-Leaf "L"
Soda chlorate
Tumbleaf
Tumbleleaf
United Chemical Defoliant No. 1
Chemical Function
Bleaching agent
Deodorizer
Oxidizing agent
Biocide
Chemical reaction regulator
Regulatory Lists
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; applied; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; applied; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; applied; Pesticides
active_ingredient; agricultural; applied; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1559268
Adverse Event Associations
29
Frequently Asked Questions
Is Sodium Chlorate allowed in the EU?
Sodium Chlorate EU regulatory status: restricted. Maximum allowed concentration: 3%. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Chlorate do in cosmetics?
Sodium Chlorate functions as: Oxidizing agent. It is classified as a cosmetic ingredient in our database. CAS number: 7775-09-9.
What is the NOAEL for Sodium Chlorate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Chlorate is =0.003 mg/kg bw/day based on a Carcinogenicity study via oral route in Rat. A total of 10 study endpoints are available. Source: INCHEM_WHO_jecfa_jecmono_v59je01.
Is Sodium Chlorate classified as hazardous under GHS?
Sodium Chlorate carries a GHS signal word of "DANGER". Hazard statements: May cause fire or explosion; strong oxidizer Harmful if swallowed Causes damage to blood and kidneys. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Is Sodium Chlorate used outside cosmetics?
Sodium Chlorate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Sodium Chlorate have different safety status in cosmetics vs industrial chemicals?
Sodium Chlorate is classified GHS Danger (H271, H302, H411, H272, H332) in the chemicals database but is restricted in EU cosmetics at max 3%.
Compliance Tools
Check Sodium Chlorate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acrylates/Vinyl Neodecanoate Crosspolymer
Excellent
Same category
Emulsion stabilising, film forming
Adipic Acid
Excellent
Same category
Buffering
Aluminum Magnesium Oxide
Excellent
Same category
Absorbent, bulking agent, opacifying ...
Ammonium VA/Acrylates Copolymer
Excellent
Same category
Antistatic, binding, film forming, ha...
Ammonium VA/Crotonic Acid Copolymer
Excellent
Same category
Antistatic, film forming, hair fixing...
Aphanothece Sacrum Polysaccharide
Excellent
Same category
Absorbent, emulsion stabilising, film...
1,2,4-Benzenetriacetate
Poor
Similar safety
Hair dye precursor (triacetyl ester o...
1,2,4-Trihydroxybenzene
Poor
Similar safety
Hair colorant (auto-oxidative dye)
1,4-Butanediol
Poor
Similar safety
Solvent, humectant, viscosity control...
1-Nitropropane
Poor
Similar safety
None in cosmetics - industrial solven...
2,3-Epoxypropyl Cocodimonium Chloride
Poor
Similar safety
Antistatic / hair conditioning agent ...
2,3-Epoxypropyl Lauryldimonium Chloride
Poor
Similar safety
Antistatic / hair conditioning agent ...
3-P-Cumenyl Propionaldehyde
Moderate
Chemical family
Fragrance
Dimethylbenzyl Carbinyl Propionate
Good
Chemical family
Fragrance ingredient with fruity and ...
Isopropylphenyl-propionaldehyde
Good
Chemical family
Fragrance (cyclamen-type floral note)
Is Sodium Chlorate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Chlorate in your formulation.