Excellent Cosmetic Ingredient NOAEL Data

Sodium Laureth-8 Sulfate

INCI: SODIUM LAURETH-8 SULFATE

CAS Number

9004-82-4

Function

Cleansing, foaming, surfactant

Safety Rating

EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted

🇺🇸 US Status permitted

US Notes Permitted; FDA UNII: YP8U3694P0; CIR-reviewed SLES class

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)

adequate

Dermal Absorption

negligible

Sensitization

high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Sodium Laureth-8 Sulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint	Value	Route	Species	Study Type	Source
NOAEL	50 mg/kg bw/day	oral	rat	oral	REACH
LOAEL	150 other	dermal	code:3484	dermal	REACH
NOAEL	50 mg/kg bw/day	oral	rat	oral	REACH
LOEL	508 mg/kg bw/day	oral	rat	oral	REACH

Expert Verdict

1,4-dioxane residual testing critical; reduced foaming efficacy compared to lower-EO SLES

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Concern Level: None

Regulatory Flags

eu_children_restricted epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is Sodium Laureth-8 Sulfate safe in cosmetics?

1,4-dioxane residual testing critical; reduced foaming efficacy compared to lower-EO SLES The EU classifies Sodium Laureth-8 Sulfate as "permitted". Safety rating: EXCELLENT. 4 toxicological study endpoint(s) are available in our database.

Is Sodium Laureth-8 Sulfate allowed in the EU?

Sodium Laureth-8 Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Laureth-8 Sulfate do in cosmetics?

Sodium Laureth-8 Sulfate functions as: Cleansing, foaming, surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 9004-82-4.

What is the Margin of Safety for Sodium Laureth-8 Sulfate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium Laureth-8 Sulfate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Laureth-8 Sulfate is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

Compliance Tools

Check Sodium Laureth-8 Sulfate compliance across multiple jurisdictions:

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Ingredient Decoder

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82 Allergen Checker

Check for EU declarable fragrance allergens

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Substance Compliance

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MoS Calculator

Calculate Margin of Safety using SCCS methodology

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Heavy Metal Limits

Compare limits across jurisdictions

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