Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Sodium Levulinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
CIR Expert Panel concluded safe as used when formulated to be non-irritating. COSMOS/ECOCERT eligible. Main caution: penetration enhancement properties for co-formulated actives.
Frequently Asked Questions
Is Sodium Levulinate safe in cosmetics?
CIR Expert Panel concluded safe as used when formulated to be non-irritating. COSMOS/ECOCERT eligible. Main caution: penetration enhancement properties for co-formulated actives. The EU classifies Sodium Levulinate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Sodium Levulinate allowed in the EU?
Sodium Levulinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Levulinate do in cosmetics?
Sodium Levulinate functions as: Skin conditioning, preservative booster, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 19856-23-6.
What is the Margin of Safety for Sodium Levulinate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Levulinate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Levulinate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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