Good Cosmetic Ingredient NOAEL Data Sensitization Data

Decylene Glycol

INCI: DECYLENE GLYCOL

CAS Number
1119-86-4
Function
Skin conditioning, antimicrobial/preservative booster, emollient, penetration enhancer
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restrictions; not a sunscreen active

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Decylene Glycol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 100 mg/kg bw/day oral rat oral REACH

Sensitization Profile

Contact sensitization data for Decylene Glycol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
preservative
EU Allergen Listed
no
Patch Test Positive Rate
0.1%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis

Source: ESSCA; IVDK; NACDG

Expert Verdict

Well-supported preservative booster with favorable safety profile via CIR class read-across from 1,2-glycols. Limited standalone data but moderate dermal absorption and low toxicity support safety at typical use levels.

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Concern Level: Low

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Decylene Glycol safe in cosmetics?

Well-supported preservative booster with favorable safety profile via CIR class read-across from 1,2-glycols. Limited standalone data but moderate dermal absorption and low toxicity support safety at typical use levels. The EU classifies Decylene Glycol as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Decylene Glycol allowed in the EU?

Decylene Glycol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decylene Glycol do in cosmetics?

Decylene Glycol functions as: Skin conditioning, antimicrobial/preservative booster, emollient, penetration enhancer. It is classified as a cosmetic ingredient in our database. CAS number: 1119-86-4.

What is the Margin of Safety for Decylene Glycol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Decylene Glycol?

The NOAEL (No Observed Adverse Effect Level) for Decylene Glycol is 100 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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