Is Silver Citrate safe in cosmetics?
Silver Citrate has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Good
Cosmetic Ingredient
Silver Citrate
INCI: SILVER CITRATE
Silver Citrate (CAS 126-45-4) is a cosmetic cosmetic ingredient functioning as Preservative, antimicrobial agent, deodorant active. EU Regulation 1223/2009 status: restricted, max 0.2%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 126-45-4 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative, antimicrobial agent, deodorant active
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
trisilver;2-hydroxypropane-1,2,3-tricarboxylate
InChIKey
QUTYHQJYVDNJJA-UHFFFAOYSA-K
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.2%
US US Status
permitted
US Notes
No specific FDA monograph; not GRASE classified; permitted without specific restrictions under MoCRA
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Silver Citrate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
6 property records from structured ingredient metadata.
acne
{"cas_number": "206986-71-0", "anti_acne_mechanism": "antibacterial", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "p_acnes_mic_ug_per_ml": "10-100", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne"…
deodorant
{"cas_number": "206986-90-5", "ingredient_class": "antimicrobial_deodorant", "mechanism_of_action": "bacterial_growth_inhibition", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "65-85", "bacteriostatic": "yes", "bactericidal": "yes", "target_bacteria": "broad_spectrum", "microbiome_impact": "broad", "axillary_microbiome_effect": "bac…
depigmentation
{"cas_number": "not established", "ingredient_class": "other", "primary_mechanism_of_action": "Mineral active providing UV protection or exfoliation preventing/treating hyperpigmentation", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduct…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "8.0", "stable_ph_min": "4.5", "stable_ph_max": "9.0", "degrades_above_ph": "9.5", "degrades_below_ph": "4.0", "ph_dependent_function": "Antimicrobial silver complex", "formulation_note": "Natural preservative system", "source": "Formulation literature"}
preservative
{"preservative_class": "Metal complex", "antimicrobial_spectrum_bacteria_gp": "Excellent", "antimicrobial_spectrum_bacteria_gn": "Excellent", "antimicrobial_spectrum_yeast": "Yes", "antimicrobial_spectrum_mold": "Moderate", "mic_staph_aureus_ppm": "20", "mic_e_coli_ppm": "18", "mic_pseudomonas_ppm": "22", "mic_candida_albicans_ppm": "80", "mic_aspergillus_niger_ppm": "200", "challenge_test_pass_co…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Expert Verdict
Expert safety assessment and concern-level summary for Silver Citrate.
Regulatory Flags
Restricted
Frequently Asked Questions
Is Silver Citrate allowed in the EU?
Silver Citrate EU regulatory status: restricted. Maximum allowed concentration: 0.2%. This is based on EU Regulation 1223/2009 and its amendments.
What does Silver Citrate do in cosmetics?
Silver Citrate functions as: Preservative, antimicrobial agent, deodorant active. It is classified as a cosmetic ingredient in our database. CAS number: 126-45-4.
Is Silver Citrate used outside cosmetics?
Silver Citrate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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