Regulatory Status
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Safety Data
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Expert Verdict
Clastogenic in vitro with metabolic activation (chromosome aberrations in V79 cells); nephrotoxicity at ≥ 300 mg/kg bw/d; dose-dependent histopathological effects in thymus, spleen, and adrenals at all tested doses; eye irritant undiluted
Regulatory Flags
Frequently Asked Questions
Is Tetraaminopyrimidine Sulfate safe in cosmetics?
Clastogenic in vitro with metabolic activation (chromosome aberrations in V79 cells); nephrotoxicity at ≥ 300 mg/kg bw/d; dose-dependent histopathological effects in thymus, spleen, and adrenals at all tested doses; eye irritant undiluted The EU classifies Tetraaminopyrimidine Sulfate as "restricted". Safety rating: MODERATE.
Is Tetraaminopyrimidine Sulfate allowed in the EU?
Tetraaminopyrimidine Sulfate EU regulatory status: restricted. Maximum allowed concentration: 3.4%. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetraaminopyrimidine Sulfate do in cosmetics?
Tetraaminopyrimidine Sulfate functions as: Hair dyeing – oxidative dye precursor (reacts with couplers to form final dye). It is classified as a cosmetic ingredient in our database. CAS number: 5392-28-9.
What is the Margin of Safety for Tetraaminopyrimidine Sulfate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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