Tetrahydropyranyloxy Phenol (Deoxyarbutin)
INCI: TETRAHYDROPYRANYLOXY PHENOL
Regulatory Status
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Safety Data
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Expert Verdict
Critical — Synthesized by removing hydroxyl groups from β-arbutin's glucose side chain ; metabolizes to hydroquinone (EU Annex II prohibited substance); SCCS opinion on β-arbutin (SCCP/1158/08) raised safety concerns that extend to deoxyarbutin ; some jurisdictions may restrict or require specific safety dossier; check latest SCCS opinion before formulating
Frequently Asked Questions
Is Tetrahydropyranyloxy Phenol (Deoxyarbutin) safe in cosmetics?
Critical — Synthesized by removing hydroxyl groups from β-arbutin's glucose side chain ; metabolizes to hydroquinone (EU Annex II prohibited substance); SCCS opinion on β-arbutin (SCCP/1158/08) raised safety concerns that extend to deoxyarbutin ; some jurisdictions may restrict or require specific safety dossier; check latest SCCS opinion before formulating The EU classifies Tetrahydropyranyloxy Phenol (Deoxyarbutin) as "permitted". Safety rating: MODERATE.
Is Tetrahydropyranyloxy Phenol (Deoxyarbutin) allowed in the EU?
Tetrahydropyranyloxy Phenol (Deoxyarbutin) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrahydropyranyloxy Phenol (Deoxyarbutin) do in cosmetics?
Tetrahydropyranyloxy Phenol (Deoxyarbutin) functions as: Skin lightening / Bleaching agent (tyrosinase inhibitor). It is classified as a cosmetic ingredient in our database. CAS number: 53936-56-4.
What is the Margin of Safety for Tetrahydropyranyloxy Phenol (Deoxyarbutin)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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