Good Cosmetic Ingredient GHS Classified

Tetrapotassium Pyrophosphate

INCI: TETRAPOTASSIUM PYROPHOSPHATE

CAS Number
7320-34-5
Function
Tartar control agent by chelating calcium and magnesium ions from saliva, preventing their deposition. Also functions as a corrosion inhibitor and pH adjuster.
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR safety assessment lists it as a corrosion inhibitor and pH adjuster.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes.
Routes of Exposure
The substance can be absorbed into the body by inhalation of dust.

Expert Verdict

Tetrapotassium Pyrophosphate is permitted in both EU and US cosmetics with adequate margin of safety for its use as a tartar control and pH adjusting agent.

⚠️
Concern Level: Low

Regulatory Flags

CMR epa_safer_alternative fda_food_additive

Frequently Asked Questions

Is Tetrapotassium Pyrophosphate safe in cosmetics?

Tetrapotassium Pyrophosphate is permitted in both EU and US cosmetics with adequate margin of safety for its use as a tartar control and pH adjusting agent. The EU classifies Tetrapotassium Pyrophosphate as "permitted". Safety rating: GOOD.

Is Tetrapotassium Pyrophosphate allowed in the EU?

Tetrapotassium Pyrophosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tetrapotassium Pyrophosphate do in cosmetics?

Tetrapotassium Pyrophosphate functions as: Tartar control agent by chelating calcium and magnesium ions from saliva, preventing their deposition. Also functions as a corrosion inhibitor and pH adjuster.. It is classified as a Cosmetic Ingredient in our database. CAS number: 7320-34-5.

What is the Margin of Safety for Tetrapotassium Pyrophosphate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Tetrapotassium Pyrophosphate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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