Is Thiamine Nitrate safe in cosmetics?
Thiamine Nitrate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Thiamine Nitrate
Also known as: Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, nitrate (1:1), 3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,β-hydroxyethylthiazolium nitrate, Aneurine mononitrate, Aneurine nitrate, Betabion mononitrate (+10 more)
INCI: THIAMINE NITRATE
Thiamine Nitrate (CAS 532-43-4) is a cosmetic cosmetic ingredient functioning as Skin conditioning, antistatic. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 532-43-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, antistatic
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol nitrate
InChIKey
UIERGBJEBXXIGO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; also GRAS as food/dietary supplement ingredient; registered in FDA databases
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Thiamine Nitrate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Softener and conditioner
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Thiamine Nitrate.
Regulatory Flags
fda_food_additive
Known Synonyms
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, nitrate (1:1)
3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,β-hydroxyethylthiazolium nitrate
Aneurine mononitrate
Aneurine nitrate
Betabion mononitrate
Vitamin B1 mononitrate
Vitamin B1 nitrate
Thiamine mononitrate
Thiamine nitrate (salt)
Thiamine, mononitrate
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyeth yl)-4-methyl-, nitrate (salt)
EC No.: 208-537-4
3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,beta-hydroxyethylthiazolium nitrate
Vitamin B(sub 1) nitrate
UNII-8K0I04919X
Chemical Function
Softener and conditioner
Flavouring and nutrient
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
THIAMINE MONONITRATE
ChEMBL ID
CHEMBL2104496
Max Phase
3
Frequently Asked Questions
Is Thiamine Nitrate allowed in the EU?
Thiamine Nitrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Thiamine Nitrate do in cosmetics?
Thiamine Nitrate functions as: Skin conditioning, antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 532-43-4.
Is Thiamine Nitrate used outside cosmetics?
Thiamine Nitrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Thiamine Nitrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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