Good Cosmetic Ingredient

Tiglic Acid

INCI: TIGLIC ACID

CAS Number
80-59-1 (trans-2-methyl-2-butenoic acid)
Function
Fragrance ingredient, masking agent; occurs naturally in essential oils; used as intermediate in ester synthesis (e.g., phenethyl tiglate)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes GRAS as a flavoring substance; permitted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Skin/eye irritant at concentrated levels; corrosive as pure acid — must be properly diluted; cis-isomer (angelic acid, CAS 565-63-9) has distinct properties and should not be confused; limited standalone cosmetic safety data — most evaluations are within the context of ester hydrolysis

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Concern Level: Low

Regulatory Flags

essential-oil fragrance-component

Frequently Asked Questions

Is Tiglic Acid safe in cosmetics?

Skin/eye irritant at concentrated levels; corrosive as pure acid — must be properly diluted; cis-isomer (angelic acid, CAS 565-63-9) has distinct properties and should not be confused; limited standalone cosmetic safety data — most evaluations are within the context of ester hydrolysis The EU classifies Tiglic Acid as "permitted". Safety rating: GOOD.

Is Tiglic Acid allowed in the EU?

Tiglic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tiglic Acid do in cosmetics?

Tiglic Acid functions as: Fragrance ingredient, masking agent; occurs naturally in essential oils; used as intermediate in ester synthesis (e.g., phenethyl tiglate). It is classified as a cosmetic ingredient in our database. CAS number: 80-59-1 (trans-2-methyl-2-butenoic acid).

What is the Margin of Safety for Tiglic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Tiglic Acid compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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