Tocophersolan

INCI: TOCOPHERSOLAN (SYNONYM: TOCOFERSOLAN, VITAMIN E TPGS)

CAS Number
9002-96-4 (also reported: 30999-06-5)
Function
Antioxidant, solubilizer, penetration enhancer
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; also FDA-approved as pharmaceutical excipient (GRAS for food use)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains PEG โ€” potential concern for 1,4-dioxane contamination from ethoxylation; ensure supplier provides purification certificates

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Concern Level: None

Frequently Asked Questions

Is Tocophersolan safe in cosmetics?

Contains PEG โ€” potential concern for 1,4-dioxane contamination from ethoxylation; ensure supplier provides purification certificates The EU classifies Tocophersolan as "permitted". Safety rating: EXCELLENT.

Is Tocophersolan allowed in the EU?

Tocophersolan EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tocophersolan do in cosmetics?

Tocophersolan functions as: Antioxidant, solubilizer, penetration enhancer. It is classified as a cosmetic ingredient in our database. CAS number: 9002-96-4 (also reported: 30999-06-5).

What is the Margin of Safety for Tocophersolan?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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