Is Tridecan-2-one safe in cosmetics?
Tridecan-2-one has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Tridecan-2-one
Also known as: EINECS 209-784-0, FEMA No. 3388, UNII-5Q35VHX26K, 2-Tridecankje, Ammonium palmitate (+5 more)
INCI: TRIDECAN-2-ONE (ALSO: METHYL UNDECYL KETONE, 2-TRIDECANONE)
Tridecan-2-one (CAS 593-08-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient; also found naturally in rue oil; herbaceous/fatty odor. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Fragrance ingredient; also found naturally in rue oil; herbaceous/fatty odor
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
tridecan-2-one
InChIKey
CYIFVRUOHKNECG-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FEMA GRAS (\#3388) for flavoring — generally considered safe
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tridecan-2-one.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
298
Source: WHO/JECFA
JECFA Evaluation
2-TRIDECANONE | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/59 | FAS 42-JECFA 51/235
Source: WHO/JECFA
JECFA Evaluation
METHYL UNDECYL KETONE | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/59 | FAS 42-JECFA 51/235
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for Tridecan-2-one — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
natural-origin
ifra_fragrance
fda_food_additive
Known Synonyms
EINECS 209-784-0
FEMA No. 3388
UNII-5Q35VHX26K
2-Tridecankje
Ammonium palmitate
FEMA 3388
Hendecyl methyl ketone
Mathyl undecyl kepoje
Methyl n-undecyl ketone
tridecanone
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
2-TRIDECANONE
ChEMBL ID
CHEMBL480097
Frequently Asked Questions
Is Tridecan-2-one allowed in the EU?
Tridecan-2-one EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tridecan-2-one do in cosmetics?
Tridecan-2-one functions as: Fragrance ingredient; also found naturally in rue oil; herbaceous/fatty odor. It is classified as a cosmetic ingredient in our database. CAS number: 593-08-8.
Is Tridecan-2-one used outside cosmetics?
Tridecan-2-one also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Tridecan-2-one compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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