Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Triethylene Glycol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 20000 ppm | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Do not use on damaged/burned skin — PEG-based ointments caused renal toxicity and contact dermatitis in burn patients . Not genotoxic or carcinogenic per CIR
Regulatory Flags
Frequently Asked Questions
Is Triethylene Glycol safe in cosmetics?
Do not use on damaged/burned skin — PEG-based ointments caused renal toxicity and contact dermatitis in burn patients . Not genotoxic or carcinogenic per CIR The EU classifies Triethylene Glycol as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Triethylene Glycol allowed in the EU?
Triethylene Glycol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Triethylene Glycol do in cosmetics?
Triethylene Glycol functions as: Fragrance ingredient, solvent, viscosity decreasing agent, humectant. It is classified as a cosmetic ingredient in our database. CAS number: 112-27-6.
What is the Margin of Safety for Triethylene Glycol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Triethylene Glycol?
The NOAEL (No Observed Adverse Effect Level) for Triethylene Glycol is 20000 ppm based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
Check Triethylene Glycol compliance across multiple jurisdictions:
Related Ingredients
Is Triethylene Glycol in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Triethylene Glycol in your formulation.