Is Trimethyl-4-nonanone safe in cosmetics?
Trimethyl-4-nonanone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Trimethyl-4-nonanone
Also known as: 4-Nonanone, 2,6,8-trimethyl-, EINECS 204-607-3, Isobutyl heptyl ketone, NSC 66186
INCI: TRIMETHYL-4-NONANONE
Trimethyl-4-nonanone (CAS 123-18-2) is a cosmetic cosmetic ingredient functioning as Perfuming / Fragrance ingredient (fruity odor profile). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Perfuming / Fragrance ingredient (fruity odor profile)
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
2,6,8-trimethylnonan-4-one
InChIKey
GFWVDQCGGDBTBS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use as fragrance; listed on IFRA Transparency List
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trimethyl-4-nonanone.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Editorial summary
Preliminary editorial summary for Trimethyl-4-nonanone — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
4-Nonanone, 2,6,8-trimethyl-
EINECS 204-607-3
Isobutyl heptyl ketone
NSC 66186
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3187270
Frequently Asked Questions
Is Trimethyl-4-nonanone allowed in the EU?
Trimethyl-4-nonanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trimethyl-4-nonanone do in cosmetics?
Trimethyl-4-nonanone functions as: Perfuming / Fragrance ingredient (fruity odor profile). It is classified as a cosmetic ingredient in our database. CAS number: 123-18-2.
Is Trimethyl-4-nonanone used outside cosmetics?
Trimethyl-4-nonanone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Trimethyl-4-nonanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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