Tromethamine HCl

INCI: TROMETHAMINE HCL

CAS Number
1185-53-1
Function
pH adjuster, buffering agent (protonated/acidic form of tromethamine)
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-reviewed as part of tromethamine group โ€” safe in the practices of use and concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Same nitrosamine formation precautions as tromethamine base; maintain nitrite-free storage

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Concern Level: None

Frequently Asked Questions

Is Tromethamine HCl safe in cosmetics?

Same nitrosamine formation precautions as tromethamine base; maintain nitrite-free storage The EU classifies Tromethamine HCl as "permitted". Safety rating: EXCELLENT.

Is Tromethamine HCl allowed in the EU?

Tromethamine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tromethamine HCl do in cosmetics?

Tromethamine HCl functions as: pH adjuster, buffering agent (protonated/acidic form of tromethamine). It is classified as a cosmetic ingredient in our database. CAS number: 1185-53-1.

What is the Margin of Safety for Tromethamine HCl?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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