Tyrosinase

INCI: TYROSINASE

CAS Number
9002-10-2
Function
Skin conditioning (enzyme involved in melanin biosynthesis)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed as cosmetic; permissible under general provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Pro-melanogenic enzyme โ€” could theoretically promote hyperpigmentation if active at the skin surface; must ensure intended function is conditioning rather than pigmentation alteration; verify biological activity is controlled

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is Tyrosinase safe in cosmetics?

Pro-melanogenic enzyme โ€” could theoretically promote hyperpigmentation if active at the skin surface; must ensure intended function is conditioning rather than pigmentation alteration; verify biological activity is controlled The EU classifies Tyrosinase as "permitted". Safety rating: MODERATE.

Is Tyrosinase allowed in the EU?

Tyrosinase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tyrosinase do in cosmetics?

Tyrosinase functions as: Skin conditioning (enzyme involved in melanin biosynthesis). It is classified as a cosmetic ingredient in our database. CAS number: 9002-10-2.

What is the Margin of Safety for Tyrosinase?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Tyrosinase in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Tyrosinase in your formulation.