Is Ursolic Acid safe in cosmetics?
Ursolic Acid has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Ursolic Acid
Also known as: (3beta)-3-Hydroxyurs-12-en-28-oic acid, Urs-12-en-28-oic acid, 3-hydroxy-, (3β)-, Urs-12-en-28-oic acid, 3β-hydroxy-, (3β)-3-Hydroxyurs-12-en-28-oic acid, 3β-Hydroxyurs-12-en-28-oic acid (+12 more)
INCI: URSOLIC ACID
Ursolic Acid (CAS 77-52-1) is a cosmetic cosmetic ingredient functioning as Antioxidant, skin conditioning, skin protecting, soothing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 77-52-1 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, skin conditioning, skin protecting, soothing
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
InChIKey
WCGUUGGRBIKTOS-GPOJBZKASA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use; FDA and CIR have reviewed — considered safe within recommended concentrations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ursolic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
acne
{"cas_number": "77-52-1", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_a…
anti_aging
{"anti_aging_claim": "anti-wrinkle, collagen-boosting", "mechanism_of_action": "Bioactive compound, specialized mechanism", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Yes", "elastin_protection": "Moderate", "wrinkle_reduction_pct": "12-20", "clinical_study_duration_weeks": "12", "sample_size": "35", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "J…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Fragrance
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Ursolic Acid.
Regulatory Flags
natural-origin
Known Synonyms
(3beta)-3-Hydroxyurs-12-en-28-oic acid
Urs-12-en-28-oic acid, 3-hydroxy-, (3β)-
Urs-12-en-28-oic acid, 3β-hydroxy-
(3β)-3-Hydroxyurs-12-en-28-oic acid
3β-Hydroxyurs-12-en-28-oic acid
Bungeolic acid
Malol
Merotaine
NSC 167406
NSC 4060
Neoage UR
Prunol
Ursolisome
Urson
β-Ursolic acid
EINECS No.: 201-034-0
Urs-12-en-28-oic acid, 3-hydroxy-, (3.beta.)-
Chemical Function
Deodorizer
Softener and conditioner
Fragrance
Regulatory Lists
active_ingredient; Europe; Pesticides
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
URSOLIC ACID
ChEMBL ID
CHEMBL169
Max Phase
2
Frequently Asked Questions
Is Ursolic Acid allowed in the EU?
Ursolic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ursolic Acid do in cosmetics?
Ursolic Acid functions as: Antioxidant, skin conditioning, skin protecting, soothing. It is classified as a cosmetic ingredient in our database. CAS number: 77-52-1.
Is Ursolic Acid used outside cosmetics?
Ursolic Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ursolic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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