Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for Usnic Acid based on clinical patch test studies and IFRA standards.
Source: IVDK; ESSCA; NACDG
Expert Verdict
HIGH ALERT: GHS classified H301 (toxic if swallowed), H400/H410 (very toxic to aquatic life) ; linked to acute liver failure and death when ingested orally; likelihood score B (highly likely cause of liver injury) per LiverTox ; ensure batch-to-batch consistency of concentration in topical formulas
Regulatory Flags
Frequently Asked Questions
Is Usnic Acid safe in cosmetics?
HIGH ALERT: GHS classified H301 (toxic if swallowed), H400/H410 (very toxic to aquatic life) ; linked to acute liver failure and death when ingested orally; likelihood score B (highly likely cause of liver injury) per LiverTox ; ensure batch-to-batch consistency of concentration in topical formulas The EU classifies Usnic Acid as "permitted". Safety rating: MODERATE.
Is Usnic Acid allowed in the EU?
Usnic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Usnic Acid do in cosmetics?
Usnic Acid functions as: Antimicrobial, skin conditioning, preservative-boosting. It is classified as a cosmetic ingredient in our database. CAS number: 125-46-2 (racemic); (+)-Usnic acid: 7562-61-0.
What is the Margin of Safety for Usnic Acid?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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