Good Cosmetic Ingredient NOAEL Data

VALERIANA OFFICINALIS ROOT EXTRACT

CAS Number
8057-49-6
Function
Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

4 study endpoints found for VALERIANA OFFICINALIS ROOT EXTRACT. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 18600 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 3100 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
dose_tested 18600 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
dose_tested 3100 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

VALERIANA OFFICINALIS ROOT EXTRACT is listed in the EU CosIng database with functions: Skin Conditioning It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted skin-conditioning needs-enrichment fda_food_additive

Frequently Asked Questions

Is VALERIANA OFFICINALIS ROOT EXTRACT safe in cosmetics?

VALERIANA OFFICINALIS ROOT EXTRACT is listed in the EU CosIng database with functions: Skin Conditioning It is permitted in the EU without specific restrictions. The EU classifies VALERIANA OFFICINALIS ROOT EXTRACT as "Permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is VALERIANA OFFICINALIS ROOT EXTRACT allowed in the EU?

VALERIANA OFFICINALIS ROOT EXTRACT EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does VALERIANA OFFICINALIS ROOT EXTRACT do in cosmetics?

VALERIANA OFFICINALIS ROOT EXTRACT functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 8057-49-6.

What is the NOAEL for VALERIANA OFFICINALIS ROOT EXTRACT?

The NOAEL (No Observed Adverse Effect Level) for VALERIANA OFFICINALIS ROOT EXTRACT is 18600 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: COSMOS_DB.

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