Is Veratraldehyde safe in cosmetics?
Veratraldehyde has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Veratraldehyde
Also known as: 3,4-Dimethoxybenzaldehyde, BRN 0473899, EINECS 204-373-2, FEMA No. 3109, Protocatechuecaldehyde dimethyl ether (+5 more)
INCI: VERATRALDEHYDE
Veratraldehyde (CAS 120-14-9) is a cosmetic cosmetic ingredient functioning as Perfuming (fragrance ingredient). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
Function
Perfuming (fragrance ingredient)
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
3,4-dimethoxybenzaldehyde
InChIKey
WJUFSDZVCOTFON-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FDA 21 CFR 172.515 (food flavoring — GRAS); permitted in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Veratraldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 9720 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Regulatory (6)
JECFA Number
877
Source: WHO/JECFA
JECFA Evaluation
METHYL VANILLIN | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: WHO/JECFA
JECFA Evaluation
VERATRALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: WHO/JECFA
JECFA Evaluation
VERATRIC ALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: WHO/JECFA
JECFA Evaluation
VANILLIN METHYL ETHER | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for Veratraldehyde — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
3,4-Dimethoxybenzaldehyde
BRN 0473899
EINECS 204-373-2
FEMA No. 3109
Protocatechuecaldehyde dimethyl ether
p-Veratric aldehyde
UNII-UI88P68JZD
EC No.: 204-373-2
204-373-2
VERATRUM
Chemical Function
Fragrance
No specific technical function
Flavouring and nutrient
Regulatory Lists
Australia; Food and drug - smoking-related products
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
3,4-DIMETHOXYBENZALDEHYDE
ChEMBL ID
CHEMBL1088937
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
VERATRALDEHYDE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Veratraldehyde allowed in the EU?
Veratraldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Veratraldehyde do in cosmetics?
Veratraldehyde functions as: Perfuming (fragrance ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 120-14-9.
Is Veratraldehyde used outside cosmetics?
Veratraldehyde also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Veratraldehyde compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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fragrance; solvent; anti-parasitic
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