Is ZINC GLYCINATE safe in cosmetics?
ZINC GLYCINATE has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
MODERATE
Cosmetic Ingredient
ZINC GLYCINATE
Also known as: EINECS 238-173-1, UNII-681VJX72FE, Zinc(II) glycinate, Zinc bisglycinate, Zinc Chelazome
ZINC GLYCINATE (CAS 14281-83-5) is a cosmetic cosmetic ingredient functioning as Buffering. EU Regulation 1223/2009 status: restricted, max III/24. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 14281-83-5 →
Cross-Vertical Regulatory Divergence
ZINC GLYCINATE is classified GHS Danger (H302, H315, H318, H400) in the chemicals database but is restricted in EU cosmetics at max III/24.
Source: Cosmetics: ingredients.eu status/eu max; Chemicals: ghs classifications.signal word/hazard statement code
Function
Buffering
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
zinc bis(2-aminoacetate)
InChIKey
UOXSXMSTSYWNMH-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
III/24
US US Status
restricted
US Notes
CIR: SQ - IJT 41(S2):21S
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
pH regulating agent
Editorial summary
Preliminary editorial summary for ZINC GLYCINATE — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cosing-sourced
eu-restricted
needs-enrichment
Known Synonyms
EINECS 238-173-1
UNII-681VJX72FE
Zinc(II) glycinate
Zinc bisglycinate
Zinc Chelazome
Chemical Function
pH regulating agent
Regulatory Lists
Europe; supplements
Europe; food_additive; supplements
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
7
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Zinc - Zinc Bisglycinate
Food Category
vitamins_minerals
Frequently Asked Questions
Is ZINC GLYCINATE allowed in the EU?
ZINC GLYCINATE EU regulatory status: restricted. Maximum allowed concentration: III/24. This is based on EU Regulation 1223/2009 and its amendments.
What does ZINC GLYCINATE do in cosmetics?
ZINC GLYCINATE functions as: Buffering. It is classified as a cosmetic ingredient in our database. CAS number: 14281-83-5.
Is ZINC GLYCINATE used outside cosmetics?
ZINC GLYCINATE also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does ZINC GLYCINATE have different safety status in cosmetics vs industrial chemicals?
ZINC GLYCINATE is classified GHS Danger (H302, H315, H318, H400) in the chemicals database but is restricted in EU cosmetics at max III/24.
Compliance Tools
Check ZINC GLYCINATE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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