AMINOETHYL PROPANEDIOL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for AMINOETHYL PROPANEDIOL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
AMINOETHYL PROPANEDIOL is listed in the EU CosIng database with functions: Buffering It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is AMINOETHYL PROPANEDIOL safe in cosmetics?
AMINOETHYL PROPANEDIOL is listed in the EU CosIng database with functions: Buffering It is permitted in the EU without specific restrictions. The EU classifies AMINOETHYL PROPANEDIOL as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is AMINOETHYL PROPANEDIOL allowed in the EU?
AMINOETHYL PROPANEDIOL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does AMINOETHYL PROPANEDIOL do in cosmetics?
AMINOETHYL PROPANEDIOL functions as: Buffering. It is classified as a cosmetic ingredient in our database. CAS number: 115-70-8.
What is the Margin of Safety for AMINOETHYL PROPANEDIOL?
NOAEL: 4000 mg/kg bw/day (oral; repeated‑dose study used in a cosmetic safety assessment; authors of the study considered 4000 mg/kg bw/day to be the NOAEL because observed effects at higher dose were not permanent) . | Source: CIR Expert Panel, “Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Pro... The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for AMINOETHYL PROPANEDIOL?
The NOAEL (No Observed Adverse Effect Level) for AMINOETHYL PROPANEDIOL is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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