Is AMINOETHYL PROPANEDIOL safe in cosmetics?
AMINOETHYL PROPANEDIOL has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
AMINOETHYL PROPANEDIOL
Also known as: 1,3-Propanediol, 2-amino-2-ethyl-, (1,1-Bis(hydroxymethyl)propyl)amine, 2-Amino-2-ethylpropan-1,3-diol, 2-Amino-2-ethylpropanediol, 2-Ethyl-2-amino-1,3-propanediol (+7 more)
AMINOETHYL PROPANEDIOL (CAS 115-70-8) is a cosmetic cosmetic ingredient functioning as Buffering. NOAEL 250 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 115-70-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
AMINOETHYL PROPANEDIOL is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Chemistry & Identifiers
IUPAC Name
2-amino-2-ethylpropane-1,3-diol
InChIKey
IOAOAKDONABGPZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: S - JACT 9(2):203-228, 1990
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for AMINOETHYL PROPANEDIOL.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for AMINOETHYL PROPANEDIOL across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
pH regulating agent
Expert Verdict
Expert safety assessment and concern-level summary for AMINOETHYL PROPANEDIOL.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
Known Synonyms
1,3-Propanediol, 2-amino-2-ethyl-
(1,1-Bis(hydroxymethyl)propyl)amine
2-Amino-2-ethylpropan-1,3-diol
2-Amino-2-ethylpropanediol
2-Ethyl-2-amino-1,3-propanediol
AEPD
AEPD-VOX 1000
VOX 1000
EINECS 204-101-2
2-Ethyl-2-aminopropanediol
NSC 8803
UNII-0ADF1987D4
Chemical Function
pH regulating agent
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL119482
Frequently Asked Questions
Is AMINOETHYL PROPANEDIOL allowed in the EU?
AMINOETHYL PROPANEDIOL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does AMINOETHYL PROPANEDIOL do in cosmetics?
AMINOETHYL PROPANEDIOL functions as: Buffering. It is classified as a cosmetic ingredient in our database. CAS number: 115-70-8.
Is AMINOETHYL PROPANEDIOL used outside cosmetics?
AMINOETHYL PROPANEDIOL also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does AMINOETHYL PROPANEDIOL have different safety status in cosmetics vs industrial chemicals?
AMINOETHYL PROPANEDIOL is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check AMINOETHYL PROPANEDIOL compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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