1-Naphthaleneacetic Acid

Also known as: NAA, 2-(1-Naphthyl)acetic acid, 2-(Naphthalen-1-yl)acetic acid, 2-(α-Naphthyl)ethanoic acid, Alphaspra (+14 more)

INCI: 1-NAPHTHALENEACETIC ACID

1-Naphthaleneacetic Acid (CAS 86-87-3) is a cosmetic cosmetic ingredient functioning as Skin conditioning ; primarily known as plant growth regulator (1-NAA). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 86-87-3 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning ; primarily known as plant growth regulator (1-NAA)
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C12H10O2
MW
186.21 g/mol
PubChem CID
6862
IUPAC Name
2-naphthalen-1-ylacetic acid
InChIKey
PRPINYUDVPFIRX-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not specifically regulated for cosmetics; registered as agricultural PGR in USA

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for 1-Naphthaleneacetic Acid.

Calculate MoS for your specific formulation with the MoS Calculator.

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (2)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Skin Eye Respiratory Irritation
A skin, mucous membrane, and severe eye irritant. | Dusts may cause nasal irritation.
Source: Hazardous Substances Data Bank (HSDB)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for 1-Naphthaleneacetic Acid.

Known Synonyms

NAA 2-(1-Naphthyl)acetic acid 2-(Naphthalen-1-yl)acetic acid 2-(α-Naphthyl)ethanoic acid Alphaspra Appl-set Caswell No. 589 EINECS 201-705-8 EPA Pesticide Chemical Code 056002 Floramon Fruit Fix Hormofix Klingtite Liqui-stik 1-Naphthtaleneacetic acid alpha-Naphthyleneacetic acid Niagara-stik NU-Tone Pimacol-sol

Chemical Function

Softener and conditioner

Regulatory Lists

Canada; pharmaceutical active_ingredient; Europe; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL428495
View full pharmaceutical profile →

Frequently Asked Questions

Is 1-Naphthaleneacetic Acid safe in cosmetics?

1-Naphthaleneacetic Acid has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.

Is 1-Naphthaleneacetic Acid allowed in the EU?

1-Naphthaleneacetic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 1-Naphthaleneacetic Acid do in cosmetics?

1-Naphthaleneacetic Acid functions as: Skin conditioning ; primarily known as plant growth regulator (1-NAA). It is classified as a cosmetic ingredient in our database. CAS number: 86-87-3.

Is 1-Naphthaleneacetic Acid used outside cosmetics?

1-Naphthaleneacetic Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does 1-Naphthaleneacetic Acid have different safety status in cosmetics vs industrial chemicals?

1-Naphthaleneacetic Acid is classified GHS Danger (H302, H315, H318, H319, H335, H412) in the chemicals database but is allowed in EU cosmetics.

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