Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
9 study endpoints found for Aminomethyl Propanol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=0.73 mg/kg bw/day | oral | code:3544 | oral | REACH |
| NOAEL | >=200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=2.2 mg/kg bw/day | oral | code:3544 | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 600 ppm | oral | dog | oral | REACH |
| NOAEL | >=250 ppm | oral | rat | oral | REACH |
| NOEL | >=110 ppm | oral | dog | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=3200 ppm | oral | mouse | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
pH adjuster with restricted use in EU formulations; generally recognized as safe at permitted concentrations.
Regulatory Flags
Frequently Asked Questions
Is Aminomethyl Propanol safe in cosmetics?
pH adjuster with restricted use in EU formulations; generally recognized as safe at permitted concentrations. The EU classifies Aminomethyl Propanol as "restricted". Safety rating: GOOD. 9 toxicological study endpoint(s) are available in our database.
Is Aminomethyl Propanol allowed in the EU?
Aminomethyl Propanol EU regulatory status: restricted. Maximum allowed concentration: 7%. This is based on EU Regulation 1223/2009 and its amendments.
What does Aminomethyl Propanol do in cosmetics?
Aminomethyl Propanol functions as: pH Adjuster. It is classified as a Cosmetic Ingredient in our database. CAS number: 124-68-5.
What is the Margin of Safety for Aminomethyl Propanol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Aminomethyl Propanol?
The NOAEL (No Observed Adverse Effect Level) for Aminomethyl Propanol is >=0.73 mg/kg bw/day based on a oral study via oral route in code:3544. A total of 9 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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