2-Methyl-5-Hydroxyethylaminophenol
INCI: 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for 2-Methyl-5-Hydroxyethylaminophenol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 50 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 220 mg/kg bw/day | oral | rat | oral | REACH |
Sensitization Profile
Contact sensitization data for 2-Methyl-5-Hydroxyethylaminophenol based on clinical patch test studies and IFRA standards.
Source: IVDK; NACDG; ESSCA
Expert Verdict
Prohibited in EU. In US: mandatory labeling with age restriction (not for under 16), patch test warning, and mixing ratio instructions required.
Regulatory Flags
Frequently Asked Questions
Is 2-Methyl-5-Hydroxyethylaminophenol safe in cosmetics?
Prohibited in EU. In US: mandatory labeling with age restriction (not for under 16), patch test warning, and mixing ratio instructions required. The EU classifies 2-Methyl-5-Hydroxyethylaminophenol as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is 2-Methyl-5-Hydroxyethylaminophenol allowed in the EU?
2-Methyl-5-Hydroxyethylaminophenol EU regulatory status: prohibited. Maximum allowed concentration: 1.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Methyl-5-Hydroxyethylaminophenol do in cosmetics?
2-Methyl-5-Hydroxyethylaminophenol functions as: Hair dyeing (oxidative coupler). It is classified as a cosmetic ingredient in our database. CAS number: 55302-96-0.
What is the Margin of Safety for 2-Methyl-5-Hydroxyethylaminophenol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 2-Methyl-5-Hydroxyethylaminophenol?
The NOAEL (No Observed Adverse Effect Level) for 2-Methyl-5-Hydroxyethylaminophenol is 50 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check 2-Methyl-5-Hydroxyethylaminophenol compliance across multiple jurisdictions:
Related Ingredients
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