Is 2-Nitro-N-Hydroxyethyl-P-Anisidine safe in cosmetics?
2-Nitro-N-Hydroxyethyl-P-Anisidine has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
2-Nitro-N-Hydroxyethyl-P-Anisidine
Also known as: BRN 2116308, 4-N-beta-Hydroxyethyl-amino-3-nitroanisole
INCI: 2-NITRO-N-HYDROXYETHYL-P-ANISIDINE
2-Nitro-N-Hydroxyethyl-P-Anisidine (CAS 57524-53-5) is a cosmetic cosmetic ingredient functioning as Non-oxidative hair dye (semi-permanent). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 57524-53-5 →
Auto-generated CPSR Part A draft with source citations
Function
Non-oxidative hair dye (semi-permanent)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-(4-methoxy-2-nitroanilino)ethanol
InChIKey
WCBLXRCPLCDWCS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted under coal tar hair dye exemption
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Nitro-N-Hydroxyethyl-P-Anisidine.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1287
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1287
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 2-Nitro-N-Hydroxyethyl-P-Anisidine.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
BRN 2116308
4-N-beta-Hydroxyethyl-amino-3-nitroanisole
Chemical Function
Dye
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 2-Nitro-N-Hydroxyethyl-P-Anisidine allowed in the EU?
2-Nitro-N-Hydroxyethyl-P-Anisidine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Nitro-N-Hydroxyethyl-P-Anisidine do in cosmetics?
2-Nitro-N-Hydroxyethyl-P-Anisidine functions as: Non-oxidative hair dye (semi-permanent). It is classified as a cosmetic ingredient in our database. CAS number: 57524-53-5.
Compliance Tools
Check 2-Nitro-N-Hydroxyethyl-P-Anisidine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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