Is 2,3-Xylenol (2,3-Dimethylphenol) safe in cosmetics?
2,3-Xylenol (2,3-Dimethylphenol) has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
2,3-Xylenol (2,3-Dimethylphenol)
Also known as: 4-06-00-03096, Benzene, 1,2-dimethyl-3-hydroxy-, BRN 1906267, EINECS 208-395-3, Vic-o-Xylenol (+3 more)
INCI: 2,3-XYLENOL
2,3-Xylenol (2,3-Dimethylphenol) (CAS 526-75-0) is a cosmetic cosmetic ingredient functioning as Denaturant / antimicrobial; primarily industrial - limited cosmetic relevance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 526-75-0 →
Auto-generated CPSR Part A draft with source citations
Function
Denaturant / antimicrobial; primarily industrial - limited cosmetic relevance
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
2,3-dimethylphenol
InChIKey
QWBBPBRQALCEIZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not a standard cosmetic ingredient; no specific FDA cosmetic listing
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,3-Xylenol (2,3-Dimethylphenol).
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
ICSC Safety Card
0601
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for 2,3-Xylenol (2,3-Dimethylphenol).
Regulatory Flags
ifra_fragrance
Known Synonyms
4-06-00-03096
Benzene, 1,2-dimethyl-3-hydroxy-
BRN 1906267
EINECS 208-395-3
Vic-o-Xylenol
Xyellenol 100
o-3-Xylenol
UNII-RLF9YS3586
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
IFRA Transparency
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1490403
Frequently Asked Questions
Is 2,3-Xylenol (2,3-Dimethylphenol) allowed in the EU?
2,3-Xylenol (2,3-Dimethylphenol) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,3-Xylenol (2,3-Dimethylphenol) do in cosmetics?
2,3-Xylenol (2,3-Dimethylphenol) functions as: Denaturant / antimicrobial; primarily industrial - limited cosmetic relevance. It is classified as a cosmetic ingredient in our database. CAS number: 526-75-0.
Is 2,3-Xylenol (2,3-Dimethylphenol) used outside cosmetics?
2,3-Xylenol (2,3-Dimethylphenol) also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2,3-Xylenol (2,3-Dimethylphenol) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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2,3-XYLENOL
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Chemical family
Perfuming
Atranol
Poor
Chemical family
Fragrance
EVERNIA FURFURACEA EXTRACT
Good
Chemical family
Botanical / Natural ingredient
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