Poor Fragrance Sensitization Data

Atranol

INCI: ATRANOL

CAS Number
526-37-4
Function
Fragrance
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No federal ban; voluntarily avoided by major brands; indirect exposure occurs via oakmoss and treemoss extracts

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Atranol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
yes
Patch Test Positive Rate
0.2%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis
IFRA Restricted

Source: EU 2023/1545; SCCS

Expert Verdict

EU-prohibited via Regulation 2017/1410. Occurs naturally in oakmoss and treemoss extracts; IFRA restricts combined atranol/chloroatranol to below 0.5 ppm in final fine fragrance. Do not use as standalone ingredient.

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Concern Level: High

Regulatory Flags

eu-banned annex-ii contact-allergen eu-2017-1410 natural-origin oakmoss-constituent eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Atranol safe in cosmetics?

EU-prohibited via Regulation 2017/1410. Occurs naturally in oakmoss and treemoss extracts; IFRA restricts combined atranol/chloroatranol to below 0.5 ppm in final fine fragrance. Do not use as standalone ingredient. The EU classifies Atranol as "prohibited". Safety rating: POOR.

Is Atranol allowed in the EU?

Atranol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Atranol do in cosmetics?

Atranol functions as: Fragrance. It is classified as a Fragrance in our database. CAS number: 526-37-4.

What is the Margin of Safety for Atranol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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