4-Ethoxy-M-Phenylenediamine

INCI: 4-ETHOXY-M-PHENYLENEDIAMINE

CAS Number
56272-19-4 (free base)
Function
Hair dyeing
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No current CIR assessment identified. Coal-tar hair dye exemption may technically apply under FD&C Act, but EU ban signals significant safety concern.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Banned in EU due to phenylenediamine derivative class-level sensitization and potential mutagenicity concerns. Do not formulate for any market targeting EU compliance.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is 4-Ethoxy-M-Phenylenediamine safe in cosmetics?

Banned in EU due to phenylenediamine derivative class-level sensitization and potential mutagenicity concerns. Do not formulate for any market targeting EU compliance. The EU classifies 4-Ethoxy-M-Phenylenediamine as "prohibited". Safety rating: POOR.

Is 4-Ethoxy-M-Phenylenediamine allowed in the EU?

4-Ethoxy-M-Phenylenediamine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-Ethoxy-M-Phenylenediamine do in cosmetics?

4-Ethoxy-M-Phenylenediamine functions as: Hair dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 56272-19-4 (free base).

What is the Margin of Safety for 4-Ethoxy-M-Phenylenediamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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