4-Methylpentane-2,3-Dione

Also known as: Acetyl isobutyryl

INCI: 4-METHYLPENTANE-2,3-DIONE

4-Methylpentane-2,3-Dione (CAS 7493-58-5) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 7493-58-5 →

Function
Fragrance
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not specifically restricted by FDA

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for 4-Methylpentane-2,3-Dione.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Flavouring and nutrient Fragrance
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)

Editorial summary

Preliminary editorial summary for 4-Methylpentane-2,3-Dione — not a computed safety verdict. See the sourced toxicological data above.

Regulatory Flags

fragrance-component fda_food_additive

Known Synonyms

Acetyl isobutyryl

Chemical Function

Fragrance Flavouring and nutrient

Regulatory Lists

food_additive; Substances Added to Food (formerly EAFUS) (2/2019) Europe

Australian Status

AICIS status: listed

Frequently Asked Questions

Is 4-Methylpentane-2,3-Dione safe in cosmetics?

4-Methylpentane-2,3-Dione has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.

Is 4-Methylpentane-2,3-Dione allowed in the EU?

4-Methylpentane-2,3-Dione EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-Methylpentane-2,3-Dione do in cosmetics?

4-Methylpentane-2,3-Dione functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 7493-58-5.

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