Is 4-T-Butylbenzoic Acid safe in cosmetics?
4-T-Butylbenzoic Acid has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
Poor
Cosmetic Ingredient
4-T-Butylbenzoic Acid
Also known as: Benzoic acid, 4-(1,1-dimethylethyl)-, 4-09-00-01884, BRN 0607545, EINECS 202-696-3, Kyselina p-terc.butylbenzoova (+1 more)
INCI: 4-T-BUTYLBENZOIC ACID
4-T-Butylbenzoic Acid (CAS 98-73-7) is a cosmetic cosmetic ingredient functioning as Masking agent / pH adjuster. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 98-73-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
4-T-Butylbenzoic Acid is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H360, H360F, H361, H372, H411).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Masking agent / pH adjuster
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Not specifically banned by FDA, but not commonly used; classified as a reproductive toxicant under GHS
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4-T-Butylbenzoic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
Health HazardHarmful / Irritant
Hazard Class and Category
Repr. 1B; Acute Tox. 4; STOT RE 1
Hazard Statements
- H360F
- H302 Harmful if swallowed
- H372 Causes damage to organs through prolonged or repeated exposure
Inserted via ATP: ATP03
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Cosmetic-Specific Mechanism
Category: other
Receptor targets: ERα, PPARγ
LOEC: 1 µM
EU status: restricted in nail products
modulator
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1549
(EU) 2019/831
CMR: Reprotoxic Cat. 1B()
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1549
BRIN Brazil/India Cosmetics
India: Prohibited (GNRAS)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Deodorizer
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 4-T-Butylbenzoic Acid.
Regulatory Flags
endocrine_disruptor
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
Benzoic acid, 4-(1,1-dimethylethyl)-
4-09-00-01884
BRN 0607545
EINECS 202-696-3
Kyselina p-terc.butylbenzoova
UNII-43Z7T3VN0R
Chemical Function
Biocide
Deodorizer
Regulatory Lists
banned; Europe; Personal care
detected; Europe; Other direct contact consumer goods
detected; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
artificial_sweat; detected; emissions; Europe; Other direct contact consumer goods
detected; Europe; Toys and children's products
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL93746
Frequently Asked Questions
Is 4-T-Butylbenzoic Acid allowed in the EU?
4-T-Butylbenzoic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-T-Butylbenzoic Acid do in cosmetics?
4-T-Butylbenzoic Acid functions as: Masking agent / pH adjuster. It is classified as a cosmetic ingredient in our database. CAS number: 98-73-7.
Is 4-T-Butylbenzoic Acid used outside cosmetics?
4-T-Butylbenzoic Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 4-T-Butylbenzoic Acid have different safety status in cosmetics vs industrial chemicals?
4-T-Butylbenzoic Acid is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H360, H360F, H361, H372, H411).
Compliance Tools
Check 4-T-Butylbenzoic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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