Is 4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine safe in cosmetics?
4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine
Also known as: UNII-59949U2SPD, Ethanol, 2,2'-((4,6-diamino-1,3-phenylene)bis(oxy))bis-, dihydrochloride
INCI: 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE
4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine (CAS 94082-85-6) is a cosmetic cosmetic ingredient functioning as Hair Dye (oxidative). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 94082-85-6 →
Auto-generated CPSR Part A draft with source citations
Function
Hair Dye (oxidative)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
2-[2,4-diamino-5-(2-hydroxyethoxy)phenoxy]ethanol;dihydrochloride
InChIKey
WFSSVTHTFFJDKO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Coal tar hair dye exemption applies
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1307
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1307
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine.
Regulatory Flags
potential-allergen
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
UNII-59949U2SPD
Ethanol, 2,2'-((4,6-diamino-1,3-phenylene)bis(oxy))bis-, dihydrochloride
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Frequently Asked Questions
Is 4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine allowed in the EU?
4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine do in cosmetics?
4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine functions as: Hair Dye (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 94082-85-6.
Compliance Tools
Check 4,6-Bis(2-Hydroxyethoxy)-M-Phenylenediamine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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